Impact of Interleukin 28B Genotype on the Virological Responses in Chronic Hepatitis C Treatment

AYGEN B., YILDIZ O., AKHAN S., Gunal O., TAHERİ S., ZARARSIZ G., ...Daha Fazla

GASTROENTEROLOGY RESEARCH, cilt.7, sa.5-6, ss.123-130, 2014 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7 Sayı: 5-6
  • Basım Tarihi: 2014
  • Doi Numarası: 10.14740/gr629e
  • Dergi Adı: GASTROENTEROLOGY RESEARCH
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
  • Sayfa Sayıları: ss.123-130
  • Anahtar Kelimeler: Chronic hepatitis C, Interleukin 28B, Polymorphism, Genetic, Pegylated interferon, GENETIC-VARIATION, SPONTANEOUS CLEARANCE, VIRUS-INFECTION, PLUS RIBAVIRIN, IL28B, ASSOCIATION, THERAPY, POLYMORPHISMS, MANAGEMENT, TURKEY
  • Erciyes Üniversitesi Adresli: Evet

Özet

Background: Interleukin (IL) 28B single nucleotide polymorphisms may play a role in the clearance of hepatitis C virus (HCV). We aimed to evaluate the treatment response of chronic HCV infection patients to pegile interferon (pegIFN) and ribavirin treatment with regard to IL28B rs12979860 C/T polymorphism.