SYNTHESIS AND CHARACTERIZATION OF NOVEL PYRIMIDINE DERIVATIVES FROM 2,3-FURANDIONES

Koca I., YILDIRIM I.

HETEROCYCLIC COMMUNICATIONS, vol.15, no.5, pp.377-384, 2009 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 5
  • Publication Date: 2009
  • Doi Number: 10.1515/hc.2009.15.5.377
  • Journal Name: HETEROCYCLIC COMMUNICATIONS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.377-384
  • Erciyes University Affiliated: Yes

Abstract

Various novel pyrimidine-2(1H)-one and pyrimidine-2(1H)-thione derivatives 3a-m have been synthesized efficiently in good yields by the treatment of 4-p-methylbenzoyl-5-p-methylphenyl-2,3-furandione (1a) and 4-(3,4-dimethoxybenzoyl)-5-(3,4-dimethoxyphenyl)-2,3-furandione (1b) with some ureas and thioureas 2. Structures of these compounds 3 were established on the basis of elemental analysis, IR, H-1- and C-13-NMR spectral studies.