Effects of TGF-beta 1 Overexpression on Biological Characteristics of Human Dental Pulp-derived Mesenchymal Stromal Cells


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Salkın H., Gönen Z. B. , Ergen E., Bahar D. , Çetin M.

INTERNATIONAL JOURNAL OF STEM CELLS, cilt.12, ss.170-182, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 12 Konu: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.15283/ijsc18051
  • Dergi Adı: INTERNATIONAL JOURNAL OF STEM CELLS
  • Sayfa Sayıları: ss.170-182

Özet

Objective: The aim of our study was to investigate the effect of Transforming growth factor beta-1 (TGF-beta 1) gene therapy on the surface markers, multilineage differentiation, viability, apoptosis, cell cycle, DNA damage and senescence of human Dental Pulp-derived Mesenchymal Stromal Cells (hDPSC).