Effects of TGF-beta 1 Overexpression on Biological Characteristics of Human Dental Pulp-derived Mesenchymal Stromal Cells
INTERNATIONAL JOURNAL OF STEM CELLS, cilt.12, sa.1, ss.170-182, 2019 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 12 Sayı: 1
- Basım Tarihi: 2019
- Doi Numarası: 10.15283/ijsc18051
- Dergi Adı: INTERNATIONAL JOURNAL OF STEM CELLS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.170-182
- Anahtar Kelimeler: Dental Pulp-derived Mesenchymal Stem Cells, TGF-beta 1, Proliferation, Apoptosis, Multilineage differentiation, Gene therapy
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Erciyes Üniversitesi Adresli: Evet
Özet
Objective: The aim of our study was to investigate the effect of Transforming growth factor beta-1 (TGF-beta 1) gene therapy on the surface markers, multilineage differentiation, viability, apoptosis, cell cycle, DNA damage and senescence of human Dental Pulp-derived Mesenchymal Stromal Cells (hDPSC).