Protective effects of propolis on methotrexate-induced testis injury in rat

Sonmez M. F., ÇİLENK K. T., KARABULUT D., ÜNALMIŞ S., Deligonul E., Ozturk I., ...Daha Fazla

BIOMEDICINE & PHARMACOTHERAPY, cilt.79, ss.44-51, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 79
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.biopha.2016.02.002
  • Dergi Adı: BIOMEDICINE & PHARMACOTHERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.44-51
  • Anahtar Kelimeler: Methotrexate, Propolis, HSP-70, Apoptosis, Testis, INDUCED TESTICULAR TOXICITY, INDUCED OXIDATIVE STRESS, ACID PHENETHYL ESTER, HEAT-SHOCK-PROTEIN, GERM-CELLS, OSTEOSARCOMA, GENOTOXICITY, EXPRESSION, MELATONIN, EXTRACT
  • Erciyes Üniversitesi Adresli: Evet

Özet

Propolis is an adhesive substance which is collected and used by honeybees. Propolis is a potent antioxidant and a free radical scavenger. This study was designed to determine whether propolis could protect against dysfunction and oxidative stress induced by methotrexate-induced injury in rat testis.