Increased EGFR mRNA Expression Levels in Non-Small Cell Lung Cancer


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Tasdemir S. , TAHERİ S. , AKALIN H., KONTAŞ O. , ÖNAL Ö. , ÖZKUL Y.

EURASIAN JOURNAL OF MEDICINE, cilt.51, ss.177-185, 2019 (ESCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 51 Konu: 2
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5152/eurasianjmed.2016.0237
  • Dergi Adı: EURASIAN JOURNAL OF MEDICINE
  • Sayfa Sayısı: ss.177-185

Özet

Objective: In this study, we investigated the frequency of Epidermal growth factor receptor (EGFR) gene mutations, the level of EGFR mRNA and protein expressions in Turkish population for indicating substantial differences in the frequency of EGFR mutations, EGFR amplification and EGFR protein expression between populations and the effect of these parameters in response to EGFR tyrosine kinase inhibitors.