Value of increased CRP/albumin ratio in predicting embolic events in patients with infective endocarditis

Kelesoglu Ş., Inci S., Gul M., Ozan R., Düzgün I., Tuncay A., ...Daha Fazla

BIOMARKERS IN MEDICINE, cilt.17, sa.14, ss.613-621, 2023 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 14
  • Basım Tarihi: 2023
  • Doi Numarası: 10.2217/bmm-2023-0414
  • Dergi Adı: BIOMARKERS IN MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Chemical Abstracts Core, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.613-621
  • Anahtar Kelimeler: CRP/albumin ratio, endocarditis, thromboembolism
  • Erciyes Üniversitesi Adresli: Evet

Özet

Background: The CRP/albumin ratio (CAR), a new inflammatory marker, is associated with adverse outcomes in various cardiovascular diseases. We evaluated the effectiveness of CAR in predicting embolic events in patients diagnosed with infective endocarditis (IE). Methods: A total of 145 patients with IE were included in the study and categorized into two groups according to the presence of embolic events. We retrospectively analyzed the patients' clinical, laboratory and echocardiographic data. Results: CRP (94.2 vs 63.3; p < 0.001) and CAR (25.8 vs 15.1; p < 0.001) values were significantly higher in patients who experienced embolic events. Multivariate analysis showed that a high CAR value (odds ratio: 1.030; 95% CI: 1.000-1.060; p = 0.041) was an independent predictor of embolic events in patients with IE. Conclusion: The CAR is a cheap and easily accessible marker that can predict the development of embolic events in patients diagnosed with IE.