Tractography analysis results of the trigeminus nerve, which contains fibers responsible for proprioception sensation and motor control in Adolescent Idiopathic Scoliosis

EUROPEAN SPINE JOURNAL, vol.34, pp.1-8, 2024 (SCI-Expanded)

Publication Type: Article / Article
Volume: 34
Publication Date: 2024
Doi Number: 10.1007/s00586-024-08524-y
Journal Name: EUROPEAN SPINE JOURNAL
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, MEDLINE
Page Numbers: pp.1-8
Keywords: Scoliosis, Tractography, Etiology, Brain, Cranial nerve, Magnetic resonance images
Erciyes University Affiliated: Yes

Study Design Cross-sectional Study.

Background Itisnotyetclearwhetherthelossofproprioceptivesensationandmuscleweaknessseeninadolescentidio-

pathic scoliosis (AIS) is the result of central nervous system dysfunction or secondary to spinal deformity. In our study, in

ordertofindananswertothisquestion,weexaminedthemicroarchitectureofthenervustrigeminus,whichisleastaffected

byspinaldeformityandcontainsbothproprioceptivesensoryandmotorfibers.

Methods Inthissingle-center,cross-sectionalcohortstudy,40LenkeType3(27female,13male)AISpatientsand40(25

female,15male)healthyindividualsbetweentheagesof10–18years.Tractographyofthenervustrigenimuswasperformed

using the “DSI Studio” program. The volumes of the targeted musculus pterygoideus lateralis and musculus pterygoideus

medialis were measured using the Insight Segmentation and Registration Tool Kit (ITK -SNAP) program. The data were

evaluatedusingtheStatisticalPackagefortheSocialSciences22.0programforWindows.

Results Therewasnosignificantdifferencebetweenthetwogroupsintermsofbaselinecharacteristics(p˃0.05).Leftner-

vustrigeminusfibernumberandfiberratioweresignificantlyhigherinthecontrolgroupcomparedtothescoliosisgroup

p <0.05.Rightandleftlateralpterygoidmuscleshowedlowervolumeandvolumepercentageinthescoliosisgroupcom-

pared to the control group (p <0.05).

Conclusion According to the study data, proprioceptive sensory and motor control dysfunction in AIS is predicted to develop

independently of spinal deformity.

Keywords Scoliosis · Tractography · Etiology · Brain · Cranial nerve · Magnetic resonance images