ACBID 2023 AsianAOMS Joint Congress, Antalya, Türkiye, 10 - 14 Mayıs 2023, cilt.1, sa.1, ss.117
Objective: Platelet volume indices (PVI) are group of platelet parameters that reflect platelet
morphology, such as platelet count (PLT), mean platelet volume (MPV), platelet distribution
width (PDW), plateletcrit (PCT), and platelet large cell ratio (P-LCR). In the literature, the
correlation between platelet indices parameters and inflammatory diseases such as rheumatoid
arthritis, ankylosing spondylitis, and diabetes mellitus have been reported. The aim of this
study was to evaluate the effects of platelet indices on postoperative pain and edema after
bimaxillary surgery.
Materials-Methods: This was a retrospective study included 50 patients who underwent
bimaxillary surgery at the Department of Oral and Maxillofacial Surgery, Erciyes University
Faculty of Dentistry between 2019 and 2020. Postoperative pain was assessed by intravenous
(IV) analgesic intaken, also edema was evaluated on 3D images. The correlation between
platelet indices, postoperative pain, edema, and other clinical factors were analyzed using
Lasso analysis.
Results: There was a statistically significant positive correlation between PLT and postoperative
edema on the first(T1-0) and third(T3-0) days (p< 0,001). A positive significant correlation
was found between PCT and PLT and analgesic intaken in the first 24 hours postoperatively
(p<0.001).
Conclusion: Platelet indices such as PLT and PCT may serve as potential biomarkers to predict
and manage postoperative complications in orthognathic surgery. Predictability of edema and
pain contributes to the enhanced recovery after surgery.
Keywords: Orthognathic surgery, platelets, post-operative edema