Crystal structure and Hirshfeld surface analysis of 5-amino-5 '-bromo-2 '-oxo-2,3-dihydro-1H-spiro[imidazo[1,2-a]pyridine-7,3 '-indoline]-6,8-dicarbo-nitrile dimethyl sulfoxide disolvate

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Naghiyev F. N., Khrustalev V. N., Novikov A. P., AKKURT M., Rzayev R. M., Akobirshoeva A. A., ...More

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, vol.78, pp.554-565, 2022 (ESCI)

• Publication Type: Article / Article
• Volume: 78
• Publication Date: 2022
• Doi Number: 10.1107/s2056989022004741
• Journal Name: ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
• Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
• Page Numbers: pp.554-565
• Keywords: crystal structure, spiro[imidazo[1,2-a]pyridine, hydrogen bonds, dimethyl sulfoxide, disorder, Hirshfeld surface analysis
• Erciyes University Affiliated: Yes

Abstract

In the title compound, C16H11BrN6O center dot 2C(2)H(6)OS, the 1,2,3,7-tetrahydroimidazo[1,2-a]pyridine ring system and the oxindole moiety are both nearly planar [maximum deviations = 0.042 (2) and 0.115 (2) angstrom, respectively] and their planes form a dihedral angle of 86.04 (5)degrees with each other. Intermolecular N-H center dot center dot center dot O, C-H center dot center dot center dot O and C-H center dot center dot center dot N hydrogen bonds link molecules in the crystal through the O atoms of the solvent molecules, generating a three-dimensional network. A Hirshfeld surface analysis was performed to further analyse the intermolecular interactions.