Evaluations of Corneas in Eyes with Isolated Iris Coloboma

Hashas A. S. K., Arifoglu H. B., Yuce Y., Duru N., Ulusoy D. M., ZARARSIZ G.

CURRENT EYE RESEARCH, cilt.42, sa.1, ss.41-46, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42 Sayı: 1
  • Basım Tarihi: 2017
  • Doi Numarası: 10.3109/02713683.2016.1151054
  • Dergi Adı: CURRENT EYE RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.41-46
  • Anahtar Kelimeler: Coloboma, iris, cornea, ENDOTHELIAL-CELL-DENSITY, OCULAR COLOBOMA, MORPHOLOGY, MICROSCOPY, DIAMETER
  • Erciyes Üniversitesi Adresli: Evet

Özet

Purpose: We aimed to evaluate the differences in the corneas of eyes with isolated iris coloboma.Methods: This study was designed as a prospective study. Among patients who applied to our hospital within the last 3-year period, those with isolated iris coloboma in one eye and a completely normal contralateral eye were included in the study. In addition to a complete ophthalmologic examination, all patients were scanned by Pentacam Scheimpflug camera in the dark, and a corneal endothelium cell count was taken using a Topcon Specular Microscope. Data entered using SPSS software were then evaluated by paired t-test; p < 0.05 value was considered statistically significant.Results: Nine patients, seven men and two women, with a mean age of 35.77 22.50 (range 8-60) years, were included in the study. In comparison to normal eyes, the colobomatous eyes were statistically found to have lower keratometry values in diopters (43.82 +/- 2.17, 44.46 +/- 1.86; p = 0.040), a greater negative asphericity (Q value) (-0.38 +/- 0.07, -0.22 +/- 0.20; p = 0.042), increased corneal thickness (569.78 +/- 25.42, 537.33 +/- 27.36; p < 0.001), decreased anterior chamber depth (2.50 +/- 0.32, 2.81 +/- 0.50; p = 0.005), a shallower angle (30.51 +/- 10.68, 35.29 +/- 9.99; p = 0.057), higher best-fit sphere (BFS) values of the anterior and posterior corneal surfaces (7.88 +/- 0.39, 7.67 +/- 0.37; p = 0.001; 6.40 +/- 0.26, 6.23 +/- 0.19; p = 0.006), larger pupil diameter (3.48 +/- 0.49, 2.80 +/- 0.34; p = 0.001), smaller horizontal corneal diameter (HCD) (11.06 +/- 0.42; 11.26 +/- 0.45; p = 0.009), and higher value of endothelial cell density (ECD) (3161 +/- 431; 2923 +/- 590; p = 0.031).Conclusion: We have determined that a number of factors such as keratometry values, particularly of the corneal endothelium, are different from those of normal eyes. These differences should be taken into account in the follow-up and treatment of eyes with iris coloboma.