Effects of colchicine on gingival inflammation, apoptosis, and alveolar bone loss in experimental periodontitis

Aral C. A., Aral K., Yay A. H., Ozcoban Ö., BERDELİ A., SARAYMEN R.

JOURNAL OF PERIODONTOLOGY, vol.89, no.5, pp.577-585, 2018 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 89 Issue: 5
  • Publication Date: 2018
  • Doi Number: 10.1002/jper.17-0359
  • Journal Name: JOURNAL OF PERIODONTOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.577-585
  • Keywords: apoptosis, colchicine, inflammation, oxidative stress, periodontitis, FAMILIAL MEDITERRANEAN-FEVER, AGGREGATIBACTER-ACTINOMYCETEMCOMITANS, LIGAMENT FIBROBLASTS, ORGAN-CULTURE, IN-VIVO, RATS, CELLS, EXPRESSION, ASSOCIATION, ANTIOXIDANT
  • Erciyes University Affiliated: Yes

Abstract

Background: The aim of the study was to investigate the effects of colchicine on cytokine production, apoptosis, alveolar bone loss, and oxidative stress in an experimental model of periodontitis in rats.