The effect of different doses of flumazenil on acetaminophen toxicity in rats

Bozoğluer, Emine; MADENOĞLU, HALİT; AKSU, RECEP; BİÇER, CİHANGİR; YAZICI, CEVAT; BOYACI, Adem

doi:10.4149/bll_2012_118

The effect of different doses of flumazenil on acetaminophen toxicity in rats

Atıf İçin Kopyala

Bozoğluer E., MADENOĞLU H., AKSU R., BİÇER C., YAZICI C., BOYACI A.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.113, sa.9, ss.525-528, 2012 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 113 Sayı: 9
Basım Tarihi: 2012
Doi Numarası: 10.4149/bll_2012_118
Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.525-528
Erciyes Üniversitesi Adresli: Evet

Özet

Background: Acetaminophen is an analgesic drug that is used safely in therapeutic doses. At high doses, it causes hepatotoxicity, resulting in hepatic necrosis. Some medications and methods are available for treatment of acetaminophen overdose. However, results are inconsistent, and sufficient outcomes cannot always be obtained.