The effect of different doses of flumazenil on acetaminophen toxicity in rats


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Bozoğluer E. , MADENOĞLU H. , AKSU R. , BİÇER C. , YAZICI C. , BOYACI A.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.113, ss.525-528, 2012 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 113 Konu: 9
  • Basım Tarihi: 2012
  • Doi Numarası: 10.4149/bll_2012_118
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Sayfa Sayıları: ss.525-528

Özet

Background: Acetaminophen is an analgesic drug that is used safely in therapeutic doses. At high doses, it causes hepatotoxicity, resulting in hepatic necrosis. Some medications and methods are available for treatment of acetaminophen overdose. However, results are inconsistent, and sufficient outcomes cannot always be obtained.