Metal Organic Framework-Based Dispersive Solid-Phase Microextraction of Carbaryl from Food and Water Prior to Detection by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry

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Habila M. A., Alhenaki B., El-Marghany A., Sheikh M., Ghfar A. A., ALOthman Z. A., ...More

SEPARATIONS, vol.9, no.2, 2022 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 9 Issue: 2
  • Publication Date: 2022
  • Doi Number: 10.3390/separations9020032
  • Journal Name: SEPARATIONS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Directory of Open Access Journals
  • Keywords: metal organic frameworks, dispersive solid-phase microextraction (DSPME), carbaryl, ultra-performance liquid chromatography-tandem mass spectrometry, food, water, PESTICIDE-RESIDUES, ACTIVATED CARBON, EDIBLE OILS, EXTRACTION, SAMPLES, VEGETABLES, PRECONCENTRATION, SEPARATION, IONS, INSECTICIDES
  • Erciyes University Affiliated: Yes


In this work, metal organic frameworks (A100 Al-based MOFs) were used in dispersive solid-phase microextraction (DSPME) for the isolation and preconcentration of the carbaryl from vegetable, fruit and water samples. The A100 Al-based MOFs showed excellent behavior for the adsorption of carbaryl from a water-ethanol solution; additionally, carbaryl was easily desorbed with ethyl acetate for detection by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-TMS). The analytical process of DSPME together with UPLC-TMS provides the accurate monitoring of trace carbaryl residues. The results show that the optimal recovery% of carbaryl was obtained at a sample apparent pH of 5, with the application of 1 mL of ethyl acetate to elute the carbaryl from the A100 Al-based MOFs. The limit of detection (LOD) and the limit of quantification (LOQ) were 0.01 mg.L-1 and 0.03 mg.L-1, respectively. The RSD% was 0.8-1.9, and the preconcentration factor was 45. DSPME and UPLC-TMS were successfully used for the isolation and detection of carbaryl in food and water samples.