Omega-3 fatty acids may be harmful to thickness of aortic intima-media


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BASTUG O. , KORKMAZ L. , HALIS H. , CANÖZ Ö. , GÜNEŞ T.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.116, no.4, pp.236-240, 2015 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 116 Issue: 4
  • Publication Date: 2015
  • Doi Number: 10.4149/bll_2015_046
  • Title of Journal : BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Page Numbers: pp.236-240

Abstract

There are several studies confirming an association between nicotine exposure and increase in aortic intima-media thickness (aIMT) as a pre-atherosclerotic lesion. The omega-3 FAs are on the other hand reported to have an anti-atherogenic effect. We aimed to evaluate histopathologically the effect of nicotine exposure during pregnancy and lactation period on fetal growth and aIMT at postnatal 45 days of age in rat pups living in the same conditions and to determine the protective effect of omega-3 FAs.