Association between liver fibrosis and coronary heart disease risk in patients with nonalcoholic fatty liver disease

Dogan S., Celikbilek M., Yilmaz Y. K., Sarikaya S., Zararsiz G., Serin H. I., ...Daha Fazla

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, cilt.27, sa.3, ss.298-304, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 3
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1097/meg.0000000000000286
  • Dergi Adı: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.298-304
  • Anahtar Kelimeler: cardiovascular risk, fatty liver, fibrosis, Framingham risk score, nonalcoholic fatty liver disease, nonalcoholic fatty liver disease fibrosis score, CAROTID ATHEROSCLEROSIS, SCORE, DIAGNOSIS, PREDICTION, MANAGEMENT, MORTALITY, MARKERS, EVENTS, BIOPSY, NAFLD
  • Erciyes Üniversitesi Adresli: Hayır

Özet

Background Nonalcoholic fatty liver disease (NAFLD) is being increasingly recognized as the most common cause of chronic liver disease worldwide. It has been shown that NAFLD in adults is associated with increased risk of coronary heart disease (CHD). Because of the limitations of liver biopsy, noninvasive scoring indexes such as the NAFLD fibrosis score (NFS) were developed. The Framingham risk score (FRS) provides an estimate of CHD risk. In our study we aimed to investigate whether the severity of liver fibrosis estimated with the NFS is associated with a higher risk of CHD among individuals with ultrasonography-diagnosed NAFLD.