Association between liver fibrosis and coronary heart disease risk in patients with nonalcoholic fatty liver disease

Dogan S., Celikbilek M., Yilmaz Y. K., Sarikaya S., Zararsiz G., Serin H. I., ...More

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, vol.27, no.3, pp.298-304, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 3
  • Publication Date: 2015
  • Doi Number: 10.1097/meg.0000000000000286
  • Journal Name: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.298-304
  • Keywords: cardiovascular risk, fatty liver, fibrosis, Framingham risk score, nonalcoholic fatty liver disease, nonalcoholic fatty liver disease fibrosis score, CAROTID ATHEROSCLEROSIS, SCORE, DIAGNOSIS, PREDICTION, MANAGEMENT, MORTALITY, MARKERS, EVENTS, BIOPSY, NAFLD
  • Erciyes University Affiliated: No

Abstract

Background Nonalcoholic fatty liver disease (NAFLD) is being increasingly recognized as the most common cause of chronic liver disease worldwide. It has been shown that NAFLD in adults is associated with increased risk of coronary heart disease (CHD). Because of the limitations of liver biopsy, noninvasive scoring indexes such as the NAFLD fibrosis score (NFS) were developed. The Framingham risk score (FRS) provides an estimate of CHD risk. In our study we aimed to investigate whether the severity of liver fibrosis estimated with the NFS is associated with a higher risk of CHD among individuals with ultrasonography-diagnosed NAFLD.