Lack of relationship between 17-hydroxyprogesterone response to buserelin testing and hyperinsulinemia in polycystic ovary syndrome


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Sahin Y. , Ayata D., Kelestimur F.

EUROPEAN JOURNAL OF ENDOCRINOLOGY, cilt.136, ss.410-415, 1997 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 136 Konu: 4
  • Basım Tarihi: 1997
  • Doi Numarası: 10.1530/eje.0.1360410
  • Dergi Adı: EUROPEAN JOURNAL OF ENDOCRINOLOGY
  • Sayfa Sayısı: ss.410-415

Özet

Objective: To determine whether hyperinsulinism affects cytochrome P450c17 alpha activity by investigating the correlation between 17-hydroxyprogesterone (17-OHP) hyper-responsiveness to the gonadotropin-releasing hormone (GnRH) agonist, buserelin, and the insulin response to oral glucose in polycystic ovary syndrome (PCOS).