Lack of relationship between 17-hydroxyprogesterone response to buserelin testing and hyperinsulinemia in polycystic ovary syndrome

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Sahin Y., Ayata D., Kelestimur F.

EUROPEAN JOURNAL OF ENDOCRINOLOGY, vol.136, no.4, pp.410-415, 1997 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 136 Issue: 4
  • Publication Date: 1997
  • Doi Number: 10.1530/eje.0.1360410
  • Journal Name: EUROPEAN JOURNAL OF ENDOCRINOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.410-415
  • Erciyes University Affiliated: Yes

Abstract

Objective: To determine whether hyperinsulinism affects cytochrome P450c17 alpha activity by investigating the correlation between 17-hydroxyprogesterone (17-OHP) hyper-responsiveness to the gonadotropin-releasing hormone (GnRH) agonist, buserelin, and the insulin response to oral glucose in polycystic ovary syndrome (PCOS).