Hyperpolarization techniques are key to extending the capabilities of MRI for the investigation of structural, functional and metabolic processes invivo. Recent heterogeneous catalyst development has produced high polarization in water using parahydrogen with biologically relevant contrast agents. A heterogeneous ligand-stabilized Rh catalyst is introduced that is capable of achieving N-15 polarization of 12.2 +/- 2.7% by hydrogenation of neurine into a choline derivative. This is the highest N-15 polarization of any parahydrogen method in water to date. Notably, this was performed using a deuterated quaternary amine with an exceptionally long spin-lattice relaxation time (T-1) of 21.0 +/- 0.4 min. These results open the door to the possibility of N-15 invivo imaging using nontoxic similar model systems because of the biocompatibility of the production media and the stability of the heterogeneous catalyst using parahydrogen-induced polarization (PHIP) as the hyperpolarization method.