The effects of streptozotocin-induced diabetes on ghrelin expression in rat testis: biochemical and immunohistochemical study


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Sonmez M. F. , KARABULUT D. , KILIÇ E. , AKALIN H., Sakalar C., Gunduz Y. , ...More

FOLIA HISTOCHEMICA ET CYTOBIOLOGICA, vol.53, no.1, pp.26-34, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 53 Issue: 1
  • Publication Date: 2015
  • Doi Number: 10.5603/fhc.a2015.0006
  • Title of Journal : FOLIA HISTOCHEMICA ET CYTOBIOLOGICA
  • Page Numbers: pp.26-34
  • Keywords: streptozotocin diabetes, rat, testis, ghrelin, gonadotropins, IHC, RT-PCR, GONADOTROPIN-SECRETION, FEMALE RATS, IN-VIVO, HORMONE, MELLITUS, REPRODUCTION, PARAMETERS, ENDOCRINE, APOPTOSIS, RECEPTOR

Abstract

Introduction. Ghrelin is a hormone which has effects on the secretion of growth hormone, gastrointestinal system, cardiovascular system, cell proliferation and reproductive system. The present study we focused on the relation between ghrelin and GHS-R1a gene expression and the regulation of their expression in the testes of diabetic rats.