Ergothioneine pretreatment protects the liver from ischemia-reperfusion injury caused by increasing hepatic heat shock protein 70

BEDIRLI, Abdulkadir; SAKRAK, Ömer; Muhtaroglu, SABAHATTİN; Soyuer, Işın; Guler, I; ERDOGAN, AR; SOZUER, ERDOĞAN

doi:10.1016/j.jss.2004.06.016

Ergothioneine pretreatment protects the liver from ischemia-reperfusion injury caused by increasing hepatic heat shock protein 70

BEDIRLI A., SAKRAK O., Muhtaroglu S., Soyuer I., Guler I., ERDOGAN A., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.122, sa.1, ss.96-102, 2004 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 122 Sayı: 1
Basım Tarihi: 2004
Doi Numarası: 10.1016/j.jss.2004.06.016
Dergi Adı: JOURNAL OF SURGICAL RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.96-102
Anahtar Kelimeler: liver, ischemia-reperfusion, ergothioneine, heat shock protein 70, OXIDATIVE DAMAGE, GENE-EXPRESSION, RAT-LIVER, IN-VIVO, APOPTOSIS, INDUCTION, TISSUES, CELL
Erciyes Üniversitesi Adresli: Evet

Özet

Background. Reperfusion of the liver after ischemia induces the expression of the heat shock genes and the synthesis of the heat shock proteins (HSP). We studied the effects of the natural antioxidant ergothioneine (EGT) treatment on the expression of HSP70 in ischemic-reperfused (IR) liver.