Triaminoguanidine-Isothiocyanate Reactions: Synthesis and Characterization Studies

13. International Drug Chemistry Conference, Antalya, Turkey, 6 - 09 February 2025, pp.21, (Summary Text)

Heterocyclic compounds are found in natural products, drugs, pigments, vitamins, coenzymes

and many biological processes. They have important roles in technological applications as well

as in pharmaceutical, biological and medical uses. Guanidines are one of the most versatile

functional groups in chemistry and containing this system have found application in a variety

of biological activities. Guanidine is described as an organo-superbase with basicity of amine

groups relative to conjugate acids and resonance stabilization, which is typically critical to its

biological effects [1]. Aminoguanidine (AMG), also known as imidamide, guanylhydrazine and

pimagedine, was obtained in 1892.