Stromal vascular fraction improves deep partial thickness burn wound healing

Atalay S., ÇORUH A., DENİZ K.

BURNS, vol.40, no.7, pp.1375-1383, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 40 Issue: 7
  • Publication Date: 2014
  • Doi Number: 10.1016/j.burns.2014.01.023
  • Journal Name: BURNS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1375-1383
  • Keywords: Deep second degree burn, Deep partial thickness burn, Burn wound, Stromal vascular fraction, Adipose tissue derived stem cell, Burn wound healing, stem cell, MESENCHYMAL STEM-CELLS, HUMAN DERMAL FIBROBLASTS, EPIDERMAL-GROWTH-FACTOR, ADIPOSE-TISSUE, SECRETORY FACTORS, BONE-MARROW, RATS, DIFFERENTIATION, TOLERANCE, PROMOTES
  • Erciyes University Affiliated: Yes

Abstract

Objective: The practice of early burn wound excision and wound closure by immediate autologous skin or skin substitutes is the preferred treatment in extensive deep partial and full-thickness burns. To date there is no proven definite medical treatment to decrease burn wound size and accelerate burn wound healing in modern clinical practice. Stromal vascular fraction is an autologous mixture that has multiple proven beneficial effects on different kinds of wounds. In our study, we investigated the effects of stromal vascular fraction on deep partial-thickness burn wound healing.