10. Uluslararası Katılımlı Erciyes Tıp Tıbbi Genetik Kongresi, Kayseri, Türkiye, 12 - 14 Haziran 2025, ss.37-38, (Özet Bildiri)
Introduction: Cryptosporidiosis is an infectious disease caused by Cryptosporidium species. In general, it was aimed to reveal the prevalence and genotypic diversity of the parasite against cyriptosporodiosis caused by Criptosporidium species by investigating the transmission between animal and human hosts at the molecular level. Therefore, the project titled “Investigation of Molecular Prevalence and Molecular Characterization of Zoonotic Criptosporidium Species in Human and Animal Hosts” was designed. Materials and Methods: For this purpose, PCR and QPCR tests were performed after DNA isolation of stool samples collected from human and animal hosts and the samples detected to be positive for Criptosporidium species were purified and sent to the company from which the service was purchased for sequence analysis. The obtained sequence information was analyzed using phylogenetic tools. Discussion: As a result of the phylogenetic examination of the samples detected positive in cat, dog and calf samples together with their breeders, it was determined that animal isolates and human isolates - within each group - had similar sequences and phylogenetic characters. It was found to be similar. The study is unique in that it is the first study to show the molecular level of transmission among dog, cat, horse, cattle and poultry groups and among those who raise them. Results: Therefore, it is thought that examining the symptoms and elucidating the relationship between symptoms and parasite genotypes will contribute to diagnostic studies as well as epidemiological studies. The data obtained will form the basis 38 | 10th Erciyes Medical Genetics Congress with International Participation | 12-14 June, 2025 of various studies to be conducted in the future.