Investigation of argyrophilic nucleolar organizing region

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Nisari M., Eroz R., Nisari M., Ertekin T., Oktay M., Kavutcu M.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.117, sa.6, ss.345-350, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 117 Sayı: 6
  • Basım Tarihi: 2016
  • Doi Numarası: 10.4149/bll_2016_068
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.345-350
  • Anahtar Kelimeler: NOR, AgNORs, ischemia-reperfusion, rDNA, MECHANISMS
  • Erciyes Üniversitesi Adresli: Evet

Özet

BACKGROUND: Ischemia/reperfusion (I/R) injury is a complex event frequently observed in vascular surgery and can cause functional and structural cell damage. Nucleolar-organizing regions (NORs) are sites of the ribosomal genes located on chromosomes and can be stained with silver when they are active. Thus these proteins are named as argyrophilic-NOR (AgNOR)-associated proteins. We aimed to investigate any possible effects of renal I/R injury on the NOR protein synthesis and association between the AgNOR proteins amount and histopathological injuring score.