Increased Bone Marrow Iron Scores Are Strongly Correlated With Elevated Serum Ferritin Levels and Poorer Survival in Patients With Iron Overload That Underwent Allogeneic Hematopoietic Stem Cell Transplantation: A Single Center Experience

Sivgin S., Nazlim S., ZARARSIZ G., Baspinar O., KAYNAR L., DENİZ K., ...More

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, vol.16, no.10, pp.582-587, 2016 (SCI-Expanded) identifier


Iron overload (IO) is one of the most important complications of chronic red blood cell transfusions in patients that receive chemotherapy or undergo hematopoieteic stem cell transplantation. Bone marrow is among the major sites of IO. This study showed that increased bone marrow iron content might predict poor survival in allogeneic hematopoietic stem cell transplantation recipients and that bone marrow evaluations prior to transplantation would be a valuable method to diagnose IO.