A molecular analysis of familial Mediterranean fever disease in a cohort of Turkish patients

Creative Commons License

DÜNDAR M., Kiraz A., Emirogullari E. F., SAATÇİ Ç., Taheri S., BAŞKOL M., ...Daha Fazla

ANNALS OF SAUDI MEDICINE, cilt.32, sa.4, ss.343-348, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 4
  • Basım Tarihi: 2012
  • Doi Numarası: 10.5144/0256-4947.2012.343
  • Dergi Adı: ANNALS OF SAUDI MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.343-348
  • Erciyes Üniversitesi Adresli: Evet

Özet

BACKGROUND AND OBJECTIVES: Familial Mediterranean fever (FMF) is an autosomal recessive disorder caused by mutations in MEFV gene, which encodes pyrin. FMF is especially prevalent among Turks, Armenians, non-Ashkenazi Jews, and Arabs. The aim of this study was to determine the frequency and spectrum of 12 MEFV mutations of these patients and any genotype-phenotype correlation in this large Turkish group.