Is it Different the Positivity Rate of Toxoplasma Gondii Antibody in HIV Patients than Population?


DEMİRASLAN H., EREN E., YAZAR S., ALP MEŞE E., DOĞANAY M.

The 7th Eurasia Congress of Infectious Diseases, Tiflis, Georgia, 30 September - 03 October 2015, pp.303

  • Publication Type: Conference Paper / Full Text
  • City: Tiflis
  • Country: Georgia
  • Page Numbers: pp.303
  • Erciyes University Affiliated: Yes

Abstract

Toxoplasma gondii is a ubiquitous coccidian parasite that causes diseases in congenitally infected infants, and in immunosuppressed population in the worldwide. The HIV positive and negative patients, over 18 year old, who admitted to the department, and who were worked anti-Toxoplasma gondii antibody (antiTGab) by using ELISA and immunofluorescence assay in Parasitology department were recruited. It was revealed results of the 147 patients who were 62 HIV positive and 85 HIV negative. Of them, male was 55.1% and, mean age was 38.7 year. The rate of male sex in patients with HIV was higher than those in patients without HIV (p=0,001).
The rate of AntiTGab positivity was detected 45.3% of the patients. There is no significant difference between HIV positive and negative patients (Table 1). However, mean age of patients was 76.2 year in antiTGab positive, and 54.7 year in antiTGab negative.This difference was significant (p=0.001). Toxoplasma encephalitis was developed in 2 of 29 HIV patients who were antiTGab positive. As a consequence, there is no significant difference between patients HIV positive and negative in terms of antiTGab positivity. The antiTGab positive people were older than those negative people. AntiTGab positive individuals may suffer from Toxoplasma encephalitis.