Potentiometric determination of pK(a) values of 1,4,5,8-tetrahydroxy-9-oxo-10-pentyl-9,10-dihydro-acridine-2,3,6,7-tetracarboxylic acid (TPAT) extracted from Laurus nobilis


Ibaoglu K., Sari H. I. , Tuzen M., Mendil D., Soylak M.

CHEMIA ANALITYCZNA, cilt.49, ss.635-642, 2004 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 49 Konu: 5
  • Basım Tarihi: 2004
  • Dergi Adı: CHEMIA ANALITYCZNA
  • Sayfa Sayıları: ss.635-642

Özet

The pK(a), values of 1,4,5,8-tetrahydroxy-9-oxo-10-pentyl-9,10-dihydro-acridine-2,3,6,7- tetracarboxylic acid (TPAT) extracted from Laurus nobilis were determined by Molspin potentiometric titration at 25degreesC in the presence of 0.1 mol dm(-3) NaCl. The pK(a) values were calculated using SUPERQUAD computer program. Initially deprotonation occurs in carboxylic groups, then at the nitrogen atom of the alkyl group, and finally at the hydroxylic groups of TPAT. The following pK(a) values were computed: 2.65, 3.36, 4.08, 5.43, 6.84, 9.30, 10.42 and 10.53.