Effects of Amrinone in an Experimental Model of Hepatic Ischemia-Reperfusion Injury


Küçük C., AKCAN A., Akyyldyz H. Y. , AKGÜN H. , Muhtaroglu S., Sozuer E.

JOURNAL OF SURGICAL RESEARCH, cilt.151, sa.1, ss.74-79, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 151 Konu: 1
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1016/j.jss.2008.02.008
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Sayfa Sayıları: ss.74-79

Özet

Background. During some surgical interventions, temporary occlusion of the hepatic blood supply may cause ischemia-reperfusion (IR) injury. Recent studies suggest that type 3 phosphodiesterase inhibitors may have a beneficial effect on liver IR injury. The aim of this study was to investigate whether amrinone, a type 3 phosphodiesterase inhibitor, could have a protective effect on liver having experimental liver IR injury.