A comparison of low-dose ACTH, glucagon stimulation and insulin tolerance test in patients with pituitary disorders
CLINICAL ENDOCRINOLOGY, cilt.82, sa.1, ss.45-52, 2015 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 82 Sayı: 1
- Basım Tarihi: 2015
- Doi Numarası: 10.1111/cen.12528
- Dergi Adı: CLINICAL ENDOCRINOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.45-52
- Erciyes Üniversitesi Adresli: Evet
Özet
ContextDiagnosis of secondary adrenal insufficiency and GH deficiency requires evaluation by dynamic stimulation tests in most cases. Although insulin tolerance test (ITT) is accepted as the gold-standard test for the evaluation of both hypothalamo-pituitary-adrenal (HPA) and (GH)-IGF-1 axes, the test is cumbersome. In clinical practice, low-dose adrenocorticotrophic hormone (ACTH) stimulation test is a sensitive, safe and easily applicable alternative to ITT. Although it takes more time, glucagon stimulation test (GST) is also a good alternative to ITT and can evaluate both axes.