The Association of Brain-Derived Neurotrophic Factor Gene Polymorphism with Obstructive Sleep Apnea Syndrome and Obesity

Yuksekkaya M., TUTAR N., Buyukoglan H., DÜNDAR M., YILMAZ I., GÜLMEZ I., ...More

LUNG, vol.194, no.5, pp.839-846, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 194 Issue: 5
  • Publication Date: 2016
  • Doi Number: 10.1007/s00408-016-9894-z
  • Journal Name: LUNG
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.839-846
  • Keywords: Neurotrophins, BDNF, Polymorphism, OSAS, Obesity
  • Erciyes University Affiliated: Yes

Abstract

Obesity represents a major risk factor for Obstructive Sleep Apnea Syndrome (OSAS). Brain-derived neurotrophic factor (BDNF) affects the mechanisms that regulate weight, eating behavior, and metabolism. This project aims to investigate the possible association of BDNF gene polymorphism with obesity and OSAS, and to contribute knowledge to the understanding of the pathophysiology of OSAS.