Carnitine concentrations in healthy and septicaemia suspected neonatal calves and its relation to passive immunty

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Gokce E., Sozmen M., Gulmez C., Bozukluhan K., Gokce G., Atakisi E., ...Daha Fazla

TURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES, cilt.45, sa.2, ss.229-237, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.3906/vet-2011-49
  • Dergi Adı: TURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.229-237
  • Anahtar Kelimeler: Carnitine, septicaemia, neonatal calves, passive immunity, colostrum/milk, SERUM LACTOFERRIN, SEPSIS, MILK, BIOMARKERS, PLASMA, HYPOGLYCEMIA, PREVALENCE, METABOLISM, MODULATION, MANAGEMENT
  • Erciyes Üniversitesi Adresli: Evet

Özet

This study was designed to determine carnitine concentrations in newborn calves with suspected septicaemia, healthy calves, and colostrum samples as well as to detect alterations in blood carnitine concentrations after colostrum intake. Carnitine concentrations were detected in both neonatal calves with suspected septicaemia (n = 195) and healthy calves (n = 10) as well as in colostrum/milk samples from their dams (n = 20). The mean carnitine concentration on the 2nd day after colostrum intake (32.61 mu mol/L) was significantly higher than that measured before colostrum intake (17.61 mu mol/L) (P < 0.05). The striking result was significantly lower mean carnitine concentration detected in calves with suspected septicaemia (17.11 mu mol/L), compared to healthy calves (24.92 mu mol/L) (P < 0.001). Apart from a sudden increase on day 7, no significant alteration was observed in colostrum/milk carnitine concentrations throughout the postpartum period. The results indicated that colostrum contained carnitine, which passed into the bloodstream of the calf by passive colostral transfer, and that a dramatic reduction in blood carnitine concentrations of calves with suspected septicaemia existed. The results might be of help in dealing with septicaemia suspected neonatal calves through both measurement of blood carnitine and, in response, to supplement such cases with carnitine.