Magnetic dispersive µ-solid phase extraction of aflatoxin M1 from milk samples using magnetic Co/NCHP/LDH nanocomposite

Shirani M., SALAMAT Q., Payam M. R., Sepahi S., SOYLAK M.

Journal of Chromatography A, cilt.1757, 2025 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 1757
  • Basım Tarihi: 2025
  • Doi Numarası: 10.1016/j.chroma.2025.466139
  • Dergi Adı: Journal of Chromatography A
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Analytical Abstracts, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, Chemical Abstracts Core, Chimica, Compendex, Environment Index, Food Science & Technology Abstracts, MEDLINE, Pollution Abstracts, Veterinary Science Database
  • Anahtar Kelimeler: Aflatoxin M1, Layered double hydroxides, Magnetic dispersive µ-solid phase extraction, Milk
  • Erciyes Üniversitesi Adresli: Evet

Özet

A novel magnetic adsorbent composed of cobalt/nitrogen-doped carbon nanohybrid particles/ZIF-8/ZIF-67 nanoparticles/layered double hydroxides was synthesized and applied for preconcentration and determination of aflatoxin M1 in different milk samples using a magnetic dispersive µSPE approach followed by high-performance liquid chromatography-florescence detection (HPLC-FLD). The synthesized adsorbent was then characterized using Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDX) techniques. The affective parameters, including pH, the adsorbent dosage, ionic strength, sample volume, and desorption conditions, were studied using a matrix-matched method. The linearity of 0.5–2000 ng Kg−1, the detection limit of 0.14 ng Kg−1, and the quantification limit of 0.45 ng Kg−1 were obtained. The intra-day (n = 6) and inter-day (5 days, n = 3) precisions were acquired at ≤3.3 % and ≤3.3 %, respectively, in which the results confirmed satisfactory reproducibility and repeatability. The relative recoveries (%) of 91.0- 99.0 were obtained with RSDs (%) ≤3.1 (n = 3).