Synthesis, characterization, and antimicrobial and catalytic activity of a new Schiff base and its metal(II) complexes

Aslan H. G., Akkoc S., Kökbudak Z., Aydin L.

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY, cilt.14, ss.2263-2273, 2017 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1007/s13738-017-1163-4
  • Dergi Adı: JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2263-2273
  • Anahtar Kelimeler: Antimicrobial activity, Schiff bases, SAR studies, Suzuki-Miyaura reaction, SULFONAMIDES, DERIVATIVES, SALTS, EXTRACTION, LIGAND
  • Erciyes Üniversitesi Adresli: Evet

Özet

We presented the synthesis of a new Schiff base and its complexes properties with some transition metal ions in this study. (1-amino-2-thioxo-4-p-tolyl-1,2-dihydropyrimidin-5-yl)(p-tolyl)methanone was synthesized as the starting material, and (1-((2-hydroxynaphthalen-1-yl)methyleneamino)-2-thioxo-4-p-tolyl-1,2-dihydropyrimidin-5-yl)(p-tolyl)methanone (Hnafmmp) (1) and its Ni(II) (2), Pd(II) (3), Pt(II) (4), Cu(II) (5), Co(II) (6) complexes were prepared using above-mentioned starting material. The structures of these new compounds (ligand and its complexes) were characterized with UV-Vis, FTIR, LC-MS, H-1 NMR, C-13 NMR, magnetic susceptibility, conductivity measurement, X-ray powder diffraction method, and thermal analyses techniques. The H-1 NMR chemical shifts of all complexes were calculated by using the gauge-invariant atomic orbital HF (3.21G) method in DMSO phases. All measured results were compared with the experimental data. The ligand and its complexes were also evaluated as antimicrobial agents against representative strains bacteria. Furthermore, we studied the catalytic activity of these compounds in Suzuki-Miyaura cross-coupling reaction in aqueous media.