Evaluation of the rs35996865 polymorphism of the ROCK1 gene in sepsis

KALE A., ŞENER E. F., Gunay N. E., Tahtasakal R., DEMİRYÜREK Ş., GÜNAY N., ...Daha Fazla

REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, cilt.68, sa.5, ss.586-590, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 68 Sayı: 5
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1590/1806-9282.20211105
  • Dergi Adı: REVISTA DA ASSOCIACAO MEDICA BRASILEIRA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, Directory of Open Access Journals
  • Sayfa Sayıları: ss.586-590
  • Anahtar Kelimeler: ROCK-I protein kinase, Single nucleotide polymorphism, Mortality, Sepsis, SEPTIC SHOCK, KINASE, ASSOCIATION, EXPRESSIONS
  • Erciyes Üniversitesi Adresli: Evet

Özet

OBJECTIVE: Sepsis is a complex and serious medical condition resulting from the activation of an innate host response to infections. The etiology of sepsis is complex and can be influenced by genetic susceptibility. The purpose of the present study was to investigate a possible association of Rhokinase 1 (ROCK1) gene polymorphism with sepsis in a Turkish population.