Angiotensin-Converting Enzyme Inhibitors Induce Cough
Turkish Thoracic Journal, vol.20, no.1, pp.36-42, 2019 (ESCI, Scopus, TRDizin)
- Publication Type: Article / Review
- Volume: 20 Issue: 1
- Publication Date: 2019
- Doi Number: 10.5152/turkthoracj.2018.18014
- Journal Name: Turkish Thoracic Journal
- Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
- Page Numbers: pp.36-42
- Keywords: Cough, angiotensin converting enzyme inhibitors, hypertension
- Erciyes University Affiliated: Yes
Abstract
Angiotensin-converting enzyme inhibitors (ACE-I) are widely used in diseases, such as hypertension, congestive heart failure, and myocardial infarction. Although these drugs are well tolerated, one out of five patients discontinues ACE-I due to drug side effects, mainly chronic cough. However, the pathogenesis of ACE-I-induced cough remains controversial and requires further study. In this review, the mechanisms that are suggested in ACE-I-induced cough pathophysiology will be discussed in detail in light of the current literature.