Magnetic Susceptibility Changes in the Basal Ganglia and Brain Stem of Patients with Wilson's Disease: Evaluation with Quantitative Susceptibility Mapping


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Doganay S., Gumus K., Koc G., Bayram A. K., Dogan M. S., ARSLAN D., ...More

MAGNETIC RESONANCE IN MEDICAL SCIENCES, vol.17, no.1, pp.73-79, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 1
  • Publication Date: 2018
  • Doi Number: 10.2463/mrms.mp.2016-0145
  • Journal Name: MAGNETIC RESONANCE IN MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.73-79
  • Keywords: quantitative susceptibility mapping, magnetic resonance imaging, Wilsons disease, copper, ENABLED DIPOLE INVERSION, CLINICAL CORRELATION, IRON ACCUMULATION, CRANIAL MRI, COPPER, DIFFERENTIATION, CONSISTENCY, IMAGE
  • Erciyes University Affiliated: Yes

Abstract

Objectives: Wilson's disease (WD) is characterized with the accumulation of copper in the liver and brain. The objective of this study is to quantitatively measure the susceptibility changes of basal ganglia and brain stem of pediatric patients with neurological WD using quantitative susceptibility mapping (QSM) in comparison to healthy controls.