ChemistrySelect, cilt.11, sa.2, 2026 (SCI-Expanded, Scopus)
In this study, organic–inorganic hybrid copper nanoflowers (NFs) were synthesized for the first time using Cu2+ ions as the inorganic component and Alkanna cappadocica root extracts as the organic component. The morphology of the NFs was characterized by field emission scanning electron microscopy (FE-SEM), while functional groups and crystal structures were analyzed using Fourier transform infrared spectroscopy (FT-IR) and X-ray diffraction (XRD). The phenolic and flavonoid contents of the NFs were lower than those of the extracts; however, theyp exhibited significant peroxidase-like catalytic activity absent in the extracts. Antioxidant activity was assessed using DPPH and ABTS assays, with IC50 values ranging from 22.7 to 580 µg/mL. Antileishmanial studies revealed concentration-dependent effects, inducing distinct morphological changes in parasites, with IC50 values between 189.5 and 571 µg/mL. These findings demonstrate a green synthesis approach for copper-based hybrid NFs with promising catalytic, antioxidant, and antileishmanial properties, suggesting their potential as novel biomedical and antiparasitic agents.