Anti-inflammatory Effects of Pelargonium endlicherianum Fenzl. Extracts in Lipopolysaccharide-stimulated Macrophages

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CUMAOĞLU A., Karatoprak G., Yerer M. B., KOŞAR M.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.15, sa.1, ss.107-115, 2018 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.4274/tjps.86580
  • Dergi Adı: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.107-115
  • Anahtar Kelimeler: Pelargonium species, inflammation, cytokines, cyclooxygenase-2, macrophages, PLACEBO-CONTROLLED TRIAL, DOUBLE-BLIND, EPS 7630, SIDOIDES, INFLAMMATION, ACTIVATION, RENIFORME, EFFICACY, ANTIBACTERIAL, GERANIACEAE
  • Erciyes Üniversitesi Adresli: Evet

Özet

Objectives: This study was designed to investigate the anti-inflammatory effects of Pelargonium endlicherianum Fenzl. and Pelargonium quercetorum Agnew. root extracts compared with the effects of commercial Pelargonium sidoides root extract by production of pro-inflammatory substances and inflammatory signal transduction on LPS-stimulated macrophages.