Anti-inflammatory Effects of Pelargonium endlicherianum Fenzl. Extracts in Lipopolysaccharide-stimulated Macrophages


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CUMAOĞLU A., Karatoprak G., Yerer M. B., KOŞAR M.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, vol.15, no.1, pp.107-115, 2018 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 1
  • Publication Date: 2018
  • Doi Number: 10.4274/tjps.86580
  • Journal Name: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.107-115
  • Keywords: Pelargonium species, inflammation, cytokines, cyclooxygenase-2, macrophages, PLACEBO-CONTROLLED TRIAL, DOUBLE-BLIND, EPS 7630, SIDOIDES, INFLAMMATION, ACTIVATION, RENIFORME, EFFICACY, ANTIBACTERIAL, GERANIACEAE
  • Erciyes University Affiliated: Yes

Abstract

Objectives: This study was designed to investigate the anti-inflammatory effects of Pelargonium endlicherianum Fenzl. and Pelargonium quercetorum Agnew. root extracts compared with the effects of commercial Pelargonium sidoides root extract by production of pro-inflammatory substances and inflammatory signal transduction on LPS-stimulated macrophages.