The relationship between different types of nutritional supportive treatment and infection in patients with diagnosis of Chronic Obstructive Pulmonary Disease


Cigdem U. K., Gamze T.

Kuwait Medical Journal, vol.53, no.1, pp.13-17, 2021 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 53 Issue: 1
  • Publication Date: 2021
  • Journal Name: Kuwait Medical Journal
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
  • Page Numbers: pp.13-17
  • Keywords: Chronic obstructive pulmonary disease, Enteral nutrition, Infection, Parenteral nutrition
  • Erciyes University Affiliated: No

Abstract

Objective: To investigate the effect of enteral (EN), parenteral (PN) and enteral-parenteral (EN+PN) nutritional support treatments on the type and location of micro-organisms produced causing infection and mortality in chronic obstructive pulmonary disease (COPD) patients treated by invasive mechanical ventilation in the Intensive Care Unit (ICU). Design: Retrospective study Setting: Bozok University Hospital. Subjects: Between January 2014 and January 2018, records of 78 COPD patients followed up in the ICU were reviewed retrospectively. Intervention: The type of nutrition, age, gender, mortality rates, albumin and procalcitonin values, duration of mechanical ventilation, length of stay in ICU and types of microorganisms were evaluated. Main outcome measure: Nutritional methods, age, sex, mortality rates, albumin and procalcitonin values, duration of mechanical ventilation and duration of stay were evaluated. Microorganism types and production sites were examined for microbiological evaluation. Results: Albumin values of the PN group were determined to be significantly lower than those of the EN and EN+PN groups (P <.001). The procalcitonin values of the EN group were significantly lower than EN+PN group (P=.003). The rates of production of any micro-organism were determined as 44.1% in the EN group, 70% in the PN group and 83.3% in the EN+PN group. The duration of mechanical ventilation and the length of stay in ICU were significantly shorter in the EN group than in the other two groups (z=2.179, P=.029) (z=2.029, P=.042). Conclusion: In patients with COPD treated with mechanical ventilation for whatever reasons, enteral nutrition could be one of the factors reducing infection rates.