Guaiane-type Sesquiterpene Lactones from Chrysophthalmum montanum


GÜRBÜZ P. , Dogan S. D. , PASAYEVA L. , Paksoy M. Y.

RECORDS OF NATURAL PRODUCTS, vol.10, no.6, pp.714-720, 2016 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 6
  • Publication Date: 2016
  • Title of Journal : RECORDS OF NATURAL PRODUCTS
  • Page Numbers: pp.714-720

Abstract

Four new guaiane-type sesquiterpene glycosides (1-4), 4 alpha-hydroxy-guai-1(10)-en-12,8 alpha-olide 2 beta-O-beta-D-glucopyranoside (1), 4 alpha-hydroxy-guai-1(10)-en-12,8 alpha-olide 2 beta-O-(6'-trans-caffeoyl)-beta-D-glucopyranoside (2), 10 alpha-hydroxy-guai-1(2)-en-12,8 alpha-olide 4 alpha-O-beta-D-glucopyranoside (3) and 10 alpha-hydroxy-guai-12,8 alpha-olide 4 beta-O-beta-D-glucopyranoside (4) and three known guaiane-type sesquiterpenes (5-7), 4 alpha,6 alpha-dihydroxy-1 beta,5 alpha,7 alpha H-guaia-9(10),11(13)-dien-12,8 alpha-olide (5), 6 alpha-acetoxy-4 alpha-hydroxy-1 beta H-guaia-9(10),11(13)-dien-12,8 alpha-olide (6), and 4 beta-10 alpha-Dihydroxy-5 alpha-guai-1(2),11(13)-dien-12,8 alpha-olide (7) were isolated from the aerial parts of Chrysophthalmum montanum (DC) Boiss. The structures of the compounds were elucidated by extensive 1D-and 2D-NMR spectroscopic analysis in combination with MS experiments.