Akademik Veri Yönetim Sistemi
Mathematical Modelling and Control, cilt.3, sa.2, ss.88-103, 2023 (ESCI)
Compared to many infectious diseases, tuberculosis has a high mortality rate. Because of this, a great deal of illustrative research has been done on the modeling and study of tuberculosis using mathematics. In this work, a mathematical model is created by taking into account the underlying presumptions of this disease. One of the main novelties of the paper is to consider two different treatment strategies namely protective treatment for the latent populations from the disease and the main treatment applied to the infected populations. This situation can be regarded as the other novelty of the paper. The susceptible, latent, infected, and recovered populations, as well as the two mentioned treatment classes, are all included in the proposed six-dimensional model’s compartmental framework. Additionally, a region that is biologically possible is presented, as well as the solution’s positivity, existence, and uniqueness. The suggested model’s solutions are carried out as numerical simulations using assumed and literature-based parameter values and analyzing its graphics. To get the results, a fourth-order Runge-Kutta numerical approach is used.