Investigation on Malondialdehyde, S100B, and Advanced Oxidation Protein Product Levels in Significant Hyperbilirubinemia and the Effect of Intensive Phototherapy on these Parameters


Sarici D. , GÜNEŞ T. , YAZICI C. , Akin M. A. , Korkmaz L. , Memur S. , ...More

PEDIATRICS AND NEONATOLOGY, vol.56, no.2, pp.95-100, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 56 Issue: 2
  • Publication Date: 2015
  • Doi Number: 10.1016/j.pedneo.2014.06.006
  • Title of Journal : PEDIATRICS AND NEONATOLOGY
  • Page Numbers: pp.95-100

Abstract

Background: The parameters of oxidative stress [advanced oxidation protein products (AOPPs), malondialdehyde (MDA), and S100B] and the effect of intensive phototherapy (PT) on these parameters have not been studied extensively in newborns with significant hyperbilirubinemia (SH). We aimed to measure the levels of MDA, S100B, and AOPPs in newborns with SH, and to compare newborns with healthy control newborns without hyperbilirubinemia on the basis of these parameters of oxidative stress. In addition, we investigated the effect of intensive PT on these parameters during the treatment of SH and report our findings for the first time in the literature.