Investigation on Malondialdehyde, S100B, and Advanced Oxidation Protein Product Levels in Significant Hyperbilirubinemia and the Effect of Intensive Phototherapy on these Parameters

Sarici D. , GÜNEŞ T. , YAZICI C. , Akin M. A. , Korkmaz L. , Memur S. , ...Daha Fazla

PEDIATRICS AND NEONATOLOGY, cilt.56, ss.95-100, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 56 Konu: 2
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.pedneo.2014.06.006
  • Sayfa Sayıları: ss.95-100


Background: The parameters of oxidative stress [advanced oxidation protein products (AOPPs), malondialdehyde (MDA), and S100B] and the effect of intensive phototherapy (PT) on these parameters have not been studied extensively in newborns with significant hyperbilirubinemia (SH). We aimed to measure the levels of MDA, S100B, and AOPPs in newborns with SH, and to compare newborns with healthy control newborns without hyperbilirubinemia on the basis of these parameters of oxidative stress. In addition, we investigated the effect of intensive PT on these parameters during the treatment of SH and report our findings for the first time in the literature.