Metformin improves endothelial function and carotid intima media thickness in patients with PCOS


KAYA M. G. , YILDIRIM S. , ÇALAPKORUR B. , AKPEK M. , ÜNLÜHİZARCI K. , Kelestimur F.

GYNECOLOGICAL ENDOCRINOLOGY, cilt.31, no.5, ss.401-405, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 31 Konu: 5
  • Basım Tarihi: 2015
  • Doi Numarası: 10.3109/09513590.2015.1006188
  • Dergi Adı: GYNECOLOGICAL ENDOCRINOLOGY
  • Sayfa Sayıları: ss.401-405

Özet

Objective: Oral contraceptive pills (OCP) are widely used for treating women with polycystic ovary syndrome (PCOS). Metformin has beneficial effects on insulin resistance and endothelial functions. The aim of this study was to investigate the effects of treatment with drospirenone/ethinyl estradiol (EE) alone or in combination with metformin on the flow-mediated vasodilatation (FMD) and carotid intima media thickness (CIMT) in women with PCOS.