Akademik Veri Yönetim Sistemi
Selcuk Dental Journal, cilt.12, sa.1, ss.149-156, 2025 (Scopus, TRDizin)
The processes of remineralization and demineralization in the oral cavity exist in a state of balance. When this balance is disrupted, carious lesions will develop. Initial carious lesions can be prevented through remineralization before cavitation occurs. This helps preserve the tooth structure without the need for challenging treatments that may arise in advanced stages of caries progression. In the context of caries prevention, in addition to the effective role of fluoride, which has been supported by many years of research, the use of bioactive formulations such as micro and nano hydroxyapatite, tricalcium phosphate, and bioactive glass is now being recommended for their biological compatibility, remineralization capacities, and ability to mimic natural processes. Recent studies on remineralization are based on biomimetic remineralization materials capable of forming apatite crystals within completely demineralized collagen fibers. Nanostructured materials possess superior properties compared to microstructured materials due to their higher surface-to-volume ratios. Examples of these nanostructured materials include calcium fluoride nanoparticles, calcium phosphate-containing nanomaterials, nanobioglass materials, and nanohydroxyapatite particles. These nanoparticle-containing biomimetic materials are becoming an essential part of minimally invasive treatments and the preservation of natural dental tissue in dentistry. They are designed to provide results that are closest to natural dental tissue and ensure the longevity of dental restorations. Biomimetic dentistry is a restorative dentistry discipline aimed at mimicking the natural structure, function, and aesthetics of teeth. Through this approach, which aims to replicate the natural tooth structure, research on adhesive restorative materials has been intensified. Consequently, restorative materials and treatment options exhibiting biomimetic properties will be examined based on the diagnosed indication related to the material loss occurring in dental tissue.