Microwave-assisted synthesis and myorelaxant activity of 9-indolyl-1,8-acridinedione derivatives

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GÜNDÜZ M. G., Isli F., El-Khouly A., Yildirim S., Fincan G. S. O., ŞİMŞEK R., ...More

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol.75, pp.258-266, 2014 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 75
• Publication Date: 2014
• Doi Number: 10.1016/j.ejmech.2014.01.059
• Journal Name: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.258-266
• Erciyes University Affiliated: Yes

Abstract

In this study a microwave-assisted method was applied for the synthesis of novel 9-(substituted indolyl)-3,4,6,7-tetrahydroacridine-1,8-(2H,5H,9H,10H)-dione derivatives. The structures of the compounds were confirmed by spectral methods including X-ray studies and elemental analysis.