Serum Vitamin D Levels Are Independently Associated With Severity of Coronary Artery Disease

Akin F., Ayca B., Kose N., Duran M., Sari M., Uysal O. K., ...Daha Fazla

JOURNAL OF INVESTIGATIVE MEDICINE, cilt.60, sa.6, ss.869-873, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 60 Sayı: 6
  • Basım Tarihi: 2012
  • Doi Numarası: 10.2310/jim.0b013e31825457cb
  • Dergi Adı: JOURNAL OF INVESTIGATIVE MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.869-873
  • Anahtar Kelimeler: coronary artery disease, 25-hydroxyvitamin D, inflammatory markers, vitamin D, C-reactive protein, C-REACTIVE PROTEIN, 25-HYDROXYVITAMIN D LEVELS, BEAM COMPUTED-TOMOGRAPHY, TYPE-2 DIABETES-MELLITUS, SMOOTH-MUSCLE CELLS, 1,25-DIHYDROXYVITAMIN D-3, D DEFICIENCY, ENDOTHELIAL DYSFUNCTION, PARATHYROID-HORMONE, D SUPPLEMENTATION
  • Erciyes Üniversitesi Adresli: Evet

Özet

Background and Objectives: Low-serum vitamin D levels have been associated with increased cardiovascular risk in the general population. We hypothesized that serum vitamin D levels would be inversely associated with inflammation and with severity of coronary atherosclerosis. We therefore investigated the link between serum vitamin D levels and (1) the extent of coronary artery disease (CAD) assessed by the Gensini score and (2) inflammatory parameters, including C-reactive protein and fibrinogen.