Serum Vitamin D Levels Are Independently Associated With Severity of Coronary Artery Disease
JOURNAL OF INVESTIGATIVE MEDICINE, cilt.60, sa.6, ss.869-873, 2012 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 60 Sayı: 6
- Basım Tarihi: 2012
- Doi Numarası: 10.2310/jim.0b013e31825457cb
- Dergi Adı: JOURNAL OF INVESTIGATIVE MEDICINE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.869-873
- Anahtar Kelimeler: coronary artery disease, 25-hydroxyvitamin D, inflammatory markers, vitamin D, C-reactive protein, C-REACTIVE PROTEIN, 25-HYDROXYVITAMIN D LEVELS, BEAM COMPUTED-TOMOGRAPHY, TYPE-2 DIABETES-MELLITUS, SMOOTH-MUSCLE CELLS, 1,25-DIHYDROXYVITAMIN D-3, D DEFICIENCY, ENDOTHELIAL DYSFUNCTION, PARATHYROID-HORMONE, D SUPPLEMENTATION
- Erciyes Üniversitesi Adresli: Evet
Özet
Background and Objectives: Low-serum vitamin D levels have been associated with increased cardiovascular risk in the general population. We hypothesized that serum vitamin D levels would be inversely associated with inflammation and with severity of coronary atherosclerosis. We therefore investigated the link between serum vitamin D levels and (1) the extent of coronary artery disease (CAD) assessed by the Gensini score and (2) inflammatory parameters, including C-reactive protein and fibrinogen.