Hypothalamic-pituitary-adrenal (HPA) axis activity in patients with CFIDS and the effect of corticosteroid treatment on HPA axis activity


OZSOY S., Izgi H. B., ASDEMİR A., TANRIVERDİ F., BAŞTÜRK M., Turan T., ...Daha Fazla

KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, cilt.19, 2009 (SCI-Expanded) identifier

Özet

Objective: Chronic fatigue immune dysfunction syndrome (CFIDS) is a debilitating disease characterized by physical and mental fatigue for at least 6 months. The etiology of CFIDS is heterogeneous. Hypothalamic-pituitary-adrenal (HPA) axis dysfunction is considered one of the underlying pathophysiological mechanisms. The results of the studies investigating HPA axis activity in CFIDS are quite conflicting. This study aimed to investigate HPA axis activity in patients with CFIDS and the effect of corticosteroid treatment on HPA axis activity.