IN VITRO COMPARISON OF THE EFFECTS OF DENTAL FILLING MATERIALS ON MOUSE FIBROBLASTS


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kılıç D., Kesim S., LİMAN N., Sumer Z., ÖZTÜRK A.

BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT, cilt.26, sa.4, ss.3155-3162, 2012 (SCI-Expanded, Scopus) identifier identifier

Özet

The choice of filling material is an important factor in the clinical success of root coverage. Therefore, the cytotoxicity of filling materials must be investigated to ensure a safe biological response. The aim of this study was to compare the response of L929 mouse fibroblasts to several glass ionomer cements (GICs), i.e. conventional GIC, resin-modified glass ionomer cement (RMGIC) and polyacid-modified resin composite (PMRC), using three different methods. 1) 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay 2) agar diffusion test, 3) scanning electron microscopy