Homeostasis model assessment is more reliable than the fasting glucose/insulin ratio and quantitative insulin sensitivity check index for assessing insulin resistance among obese children and adolescents

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Keskin M., Kurtoglu S., Kendirci M., Atabek M., Yazici C.

PEDIATRICS, cilt.115, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 115
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1542/peds.2004-1921
  • Dergi Adı: PEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: insulin resistance, children, adolescents, GLUCOSE, VALIDATION, HYPERINSULINISM, SECRETION, MARKER, GIRLS
  • Erciyes Üniversitesi Adresli: Evet

Özet

Objective. Simple fasting methods to measure insulin resistance, such as the homeostasis model assessment (HOMA), fasting glucose/insulin ratio (FGIR), and quantitative insulin sensitivity check index (QUICKI) methods, have been widely promoted for adult studies but have not been evaluated formally among children and adolescents. The aim of this study was to compare the HOMA, FGIR, and QUICKI methods for measuring insulin resistance, expressed by oral glucose tolerance test (OGTT) results, among obese children and adolescents.