The authors' goal in this study was to assess differences in knowledge about AIDS between students of natural science (NS) and social science (SS). The authors surveyed 542 students at Erciyes University in Kayseri, Turkey, regarding their knowledge of AIDS. Some differences in knowledge about AIDS (eg, regarding the virus that causes AIDS, the diagnostic test, risk factors) existed between NS and SS students. NS students were more knowledgeable about AIDS than were SS students. © 2008 Heldref Publications.